Product Details
Product Name:
Denzimol |
CAS No.:
73931-96-1 |
Purity:
100% |
Supply Ability:
10g |
Release date:
2024/11/13 |
Product Introduction
Bioactivity
名稱 | Denzimol |
描述 | Denzimol is a novel anticonvulsant compound.Denzimol is selective for tonic seizures. |
體內(nèi)活性 | Denzimol (30 mg/kg; p.o.; 14 days; mice) reduced brain concentration and anticonvulsant activity compared with non-treated mice, and t1/2 beta was significantly changed from 2.10 to 1.53 hr. Tonic hindlimb extension was completely abolished at a brain denzimol concentration higher than 15 mcg/g, whereas the minimum effective brain concentration was between 2-3 mcg/g both in acute and repeatedly treated animals. The brain concentration of denzimol is closely correlated with its anticonvulsant effect both in acute and repeatedly treated animals. Furthermore, these findings seem to suggest that the decreased anticonvulsant activity of denzimol, following repeated administrations, might be due to a development of pharmacokinetic tolerance.[4] |
存儲(chǔ)條件 | Shipping with blue ice. |
溶解度 | DMSO : 16.67 mg/mL (57.01 mM)
|
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:52977-29-4
$480.00 / 5mg
-
CAS:395104-30-0
$1160.00 / 5mg
-
CAS:71963-77-4
$55.00 / 100mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$2500.00/100mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 |