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Postion:Product Catalog >API>Antipyretic analgesics>Antigout Drugs>D-Glucosamine hydrochloride
D-Glucosamine hydrochloride
  • D-Glucosamine hydrochloride
  • D-Glucosamine hydrochloride

D-Glucosamine hydrochloride NEW

Price $6 $2 $0.8
Package 1kg 25kg 100kg
Min. Order: 1kg
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: D-Glucosamine hydrochloride CAS No.: 66-84-2
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Name: Sun

1. Product information

Names

NameD-Glucosamine hydrochloride
SynonymMore Synonyms

 D-Glucosamine hydrochloride Biological Activity

DescriptionGlucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo:
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References

[1]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.

[2]. Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706.

[3]. Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84.

 Chemical & Physical Properties

Boiling Point449.9oC at 760 mmHg
Melting Point190-194oC
Molecular FormulaC6H14ClNO5
Molecular Weight215.632
Flash Point225.9oC
Exact Mass215.056046
PSA124.01000
Index of Refraction72 ° (C=1， H2O)

 MSDS

D-Glucosamine hydrochloride MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • LZ6665000

  • CHEMICAL NAME :

  • D-Glucose, 2-amino-2-deoxy-, hydrochloride

  • CAS REGISTRY NUMBER :

  • 66-84-2

  • LAST UPDATED :

  • 199701

  • DATA ITEMS CITED :

  • 7

  • MOLECULAR FORMULA :

  • C6-H13-N-O5.Cl-H

  • MOLECULAR WEIGHT :

  • 215.66

  • WISWESSER LINE NOTATION :

  • VHYZYQYQYQ1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 15 gm/kg

  • TOXIC EFFECTS :

  • Peripheral Nerve and Sensation - sensory change involving peripheral nerve

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Subcutaneous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 6200 mg/kg

  • TOXIC EFFECTS :

  • Peripheral Nerve and Sensation - sensory change involving peripheral nerve

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 1100 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Parenteral

  • SPECIES OBSERVED :

  • Amphibian - frog

  • DOSE/DURATION :

  • 5 gm/kg

  • TOXIC EFFECTS :

  • Peripheral Nerve and Sensation - sensory change involving peripheral nerve

MUTATION DATA

  • TEST SYSTEM :

  • Fish - not otherwise specified

  • DOSE/DURATION :

  • 1000 ppm

  • REFERENCE :

  • NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 28,176,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T2043 No. of Facilities: 1651 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 16143 (estimated) No. of Female Employees: 13164 (estimated)

 Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesF: Flammable;Xi: Irritant;Xn: Harmful;
Risk PhrasesR21
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
WGK Germany2
RTECSLZ6665000
HS Code2932999099

 Synthetic Route

Total: 1 Page
Article illustration

N/A

CAS#:1242172-32-2

~%

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CAS#:58-86-6

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CAS#:50-99-7

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D-Galactose

CAS#:59-23-4

Detail
Literature: Phytochemistry, , vol. 71, # 11-12 p. 1375 - 1380
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Chitosan

CAS#:9012-76-4

~%

Article illustration

D-Glucosamine h...

CAS#:66-84-2

Literature: European Journal of Pharmacology, , vol. 579, # 1-3 p. 74 - 85
Article illustration

Bate-D-Galactos...

CAS#:3006-60-8

~%

Article illustration

D-Glucosamine h...

CAS#:66-84-2

Article illustration

N/A

CAS#:4704-14-7

Literature: Journal of the Chemical Society, , p. 81,85

 Precursor & DownStream

Precursor  2


  • Article illustration CAS#:9012-76-4
    Chitosan

  • Article illustration CAS#:3006-60-8
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DownStream  10

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    Levulinic acid

 Customs

HS Code2922399090
Summary2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles20

More Articles
The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.

FEBS J. 281(16) , 3591-608, (2014)

Glucose provides an essential nutrient source that supports glycolysis and the hexosamine biosynthesis pathway (HBP) to maintain tumour cell growth and survival. Here we investigated if short-term glu...

Qualitative and quantitative determination of peptides related to celiac disease in mixtures derived from different methods of simulated gastrointestinal digestion of wheat products.

Anal. Bioanal. Chem 406(19) , 4765-75, (2014)

During wheat digestion, gluten-derived proteolytic resistant peptides are generated, some of them involved in celiac disease. In vitro digestion models able to mimic the peptides generated in the huma...

The dissolution enhancement of piroxicam in its physical mixtures and solid dispersion formulations using gluconolactone and glucosamine hydrochloride as potential carriers.

Pharm. Dev. Technol. 20(1) , 74-83, (2015)

The solid dispersion technique is one of the most effective methods for improving the dissolution rate of poorly water-soluble drugs; however this is reliant on a suitable carrier and solvent being se...

 Synonyms

EINECS 200-638-1
MFCD00135831
Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-
Glucosamine (hydrochloride)



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137









Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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