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Postion:Product Catalog >Cystamine
Cystamine
  • Cystamine

Cystamine NEW

Price $32 $50 $72
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Cystamine CAS No.: 51-85-4
Purity: 99.41% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCystamine
DescriptionCystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.
In vitroIn human neuroblastoma SH-SY5Y cells, Cystamine inhibits the MG132-mediated and H2O2-mediated activation of caspase-3 in a concentration-dependent manner. Cystamine (250 μM) robustly results in an increasement of the glutathione level[1].
In vivoIn R6/2 transgenic HD mice, oral and intraperitoneal administration of Cystamine (112-225 mg/kg) reduces the levels of transglutaminase and N(Sigma)-(gamma-L-glutamyl)-L-lysin. Cystamine extends survival and improves body weight and motor performance[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (591.0 mM), Sonication is recommended.
KeywordsCystamine
Inhibitors RelatedTaurodeoxycholic acid | Allethrin | SKLB-163 | Fenbufen | Taurochenodeoxycholic Acid | Tauroursodeoxycholate sodium | CIL62 | Tauroursodeoxycholate | Allicin | PAC-1
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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