Product Details
Product Name:
CT52923 |
CAS No.:
205256-55-9 |
Purity:
99.88% |
Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
名稱 | CT52923 |
描述 | CT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching pathological diseases such as atherosclerosis, glomerulonephritis, liver cirrhosis, pulmonary fibrosis, and cancer. |
體外活性 | CT52923 inhibits PDGFRs and stem cell factor receptors with IC50 values of 100 to 200 nM. CT52923(0.01-30 μ M; 24 h) blocks smooth muscle cell migration or fibroblast proliferation induced by platelet-derived growth factor, IC50 is 64 and 280 nM respectively [1]. |
體內(nèi)活性 | CT52923 (oral; 5,15,30 and 50 mg/kg; twice daily) significantly inhibits the formation of neointima after carotid artery injury in rats [1]. |
存儲條件 | Shipping with blue ice. |
溶解度 | DMSO : 60 mg/mL (128.33 mM)
|
關(guān)鍵字 | CT 52923 | CT-52923 | CT52923 |
相關(guān)產(chǎn)品 | Nintedanib | Regorafenib monohydrate | Imatinib Mesylate | Sunitinib Malate | Sorafenib | Regorafenib | Nintedanib esylate | Sorafenib tosylate | Lenvatinib mesylate | Imatinib | Pazopanib | Axitinib |
相關(guān)庫 | 抗肺癌化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 酪氨酸激酶分子庫 | 激酶抑制劑庫 | 抑制劑庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |