Congo Red NEW
Price | $58 |
Package | 500mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: Congo Red | CAS No.: 573-58-0 |
Purity: 98.1% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | Congo Red |
描述 | Congo Red (Direct Red 28) is an azo dye. It binding been used as a diagnostic test for the presence of amyloid in tissue sections. |
體外活性 | Congo Red histochemical stain may serve as a tool to investigate if aggregates in mutant cells have misfolded β-pleated sheet secondary structures [1]. Congo Red dye specifically binds to crossed β-pleated sheet structures. While wild-type HSPB1 maintains protein homeostasis by binding proteins in non-native conformations and preventing aggregation, the T139M mutant fails in this function, resulting in the accumulation of misfolded proteins targeted by Congo Red for intercalation between the β-pleated sheet structures. |
存儲(chǔ)條件 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 100 mg/mL (143.54 mM), Sonication is recommended. H2O : 4.16 mg/mL (5.97 mM), Sonication and heating are recommended. |
關(guān)鍵字 | Inhibitor | inhibit | Congo Red |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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