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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Colistin sulfate
Colistin sulfate
  • Colistin sulfate

Colistin sulfate NEW

Price $48 $81
Package 100mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Colistin sulfate CAS No.: 1264-72-8
Purity: ≥95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameColistin sulfate
DescriptionColistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
In vitroIn mice, daily intramuscular injections of Colistin sulfate (15 mg/kg) result in granular degeneration in renal and hepatic epithelial tissues. Similarly, in piglets, daily intramuscular injections of Colistin sulfate (15 mg/kg) lead to significant neurotoxic effects.
In vivoColistin (2 μg/mL) exhibits broad-spectrum antibacterial activity, effectively inhibiting most strains of Escherichia coli and Pseudomonas aeruginosa, as well as all strains of the genera Enterobacter, Salmonella, Shigella, Pasteurella, Brucella, and Bordetella. Additionally, it is active against strains of the genera Moraxella, Serratia, and Providencia. In 225 strains of P. aeruginosa, the MIC90 and MIC50 of Colistin are 6.3 μg/mL and 1.6 μg/mL, respectively. In Acinetobacter baumannii, Colistin sulfate demonstrates concentration-dependent post-antibiotic effects.
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 10 mM
DMSO : Insoluble
KeywordsColistin sulfate | Polymyxin E | Autophagy | 1066-17-7 free base | Antibiotic | inhibit | Colistin | Colistin Sulfate | Inhibitor | Bacterial | 1066-17-7
Related Compound LibrariesBioactive Compound Library | Cyclic Peptide Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Microbial Natural Product Library | Natural Product Library for HTS | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
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