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Postion:Product Catalog >CM-675
CM-675
  • CM-675

CM-675 NEW

Price $58 $87 $148
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: CM-675 CAS No.: 1872466-47-1
Purity: 99.67% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱CM-675
描述CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to treat Alzheimer’s disease.
體外活性CM-675 (29a) demonstrates a pronounced time-dependent inhibitory effect on class I HDACs, particularly HDAC2. Its potency against HDAC1 also significantly enhances over time, showing increased inhibition (~1 log unit) at varying pre-incubation intervals: 673 nM at 30 minutes, 180 nM at 4 hours, and 69 nM at 6 hours[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 22.5 mg/mL (41.9 mM), Sonication and heating to 60℃ are recommended.
關(guān)鍵字CM675 | CM-675 | CM 675
相關(guān)產(chǎn)品Valproic acid sodium salt | Panobinostat | Theophylline monohydrate | Sodium 4-phenylbutyrate | Curcumin | Theobromine | Apremilast | Indomethacin | Icariin | 4-Phenylbutyric acid | Theophylline | Doxofylline
相關(guān)庫DNA 損傷和修復(fù)分子庫 | NF-κB 通路分子庫 | 經(jīng)典已知活性庫 | 表觀遺傳庫 | 染色質(zhì)修飾分子庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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