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Postion:Product Catalog >CL-82198
CL-82198
  • CL-82198

CL-82198 NEW

Price $39 $67 $155
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-13

Product Details

Product Name: CL-82198 CAS No.: 307002-71-7
Purity: 95.91% Supply Ability: 10g
Release date: 2024/11/13

Product Introduction

Bioactivity

名稱CL-82198
描述CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1’ pocket of MMP-13, ensuring its selectivity and preventing inhibition of other MMPs.
體外活性CL-82198 decreases CTGF and TGF-β1 protein levels in hepatic stellate cells[3]. CL-82198 (10 μM; 24 hours) obviously reduces LS174 cell migration[1].
體內(nèi)活性CL82198 (1-10 mg/kg; i.p.; every other day for 12 weeks) treatment avoids and decelerates MLI-induced osteoarthritis progression.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (330.72 mM), Sonication is recommended.
關(guān)鍵字CL-82198 | Inhibitor | CL82198 | MMP | inhibit | Matrix metalloproteinases | CL 82198
相關(guān)產(chǎn)品Stigmasterol | Ethyl gallate | Doxycycline (hyclate) | Chondroitin sulfate | Astragaloside IV | Doxycycline | Edaravone | Glucosamine | Triolein | Arctigenin | Fenofibric acid | Glucosamine sulfate
相關(guān)庫經(jīng)典已知活性庫 | 蛋白酶抑制劑庫 | 血管生成庫 | 抑制劑庫 | 抗纖維化化合物庫 | NO PAINS 化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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