Chlorzoxazone NEW
Price | Get Latest Price | ||
Package | ≥1kg | ≥25kg | ≥100kg |
Min. Order: | 1kg |
Supply Ability: | 20tons |
Update Time: | 2024-11-15 |
Product Details
Product Name: Chlorzoxazone | CAS No.: 95-25-0 |
EC-No.: 202-403-9 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 20tons |
Release date: 2024/11/15 |
Product name | Chlorzoxazone |
CAS | 95-25-0 |
Appearance | white powder |
Assay | 99% |
Storage | Cool and Protect from light |
Chlorzoxazone
Product Name Chlorzoxazone
CAS 95-25-0
MF C7H4ClNO2
MW 169.57
EINECS 202-403-9
MOL File 95-25-0.mol
Chemical Properties
Melting point 191-192 °C (lit.)
Density 1.3771 (rough estimate)
refractive index 1.5557 (estimate)
storage temp. room temp
solubility DMSO: soluble50mg/mL, clear
form Powder
pka pKa 8.3 (Uncertain)
color white to off-white
Water Solubility 0.1 g/100 mL
Merck 14,2194
CAS DataBase Reference 95-25-0(CAS DataBase Reference)
NIST Chemistry Reference Chlorzoxazone(95-25-0)
EPA Substance Registry System Chlorzoxazone (95-25-0)
Usage And Synthesis
Skeletal muscle relaxants
Chlorzoxazone
is an orally active central skeletal muscle relaxant with its chemical
structure being completely different with all the other muscle
relaxants. It, mainly through acting on the central cerebral cortex and
the spinal cord, inhibits the multi-synaptic reflection related to
muscle spasms and produces muscle relaxation, further relieves the spasm
caused pain and increase the flexibility of the muscles involved.
Acetaminophen belongs to non-steroidal anti-inflammatory drugs and may
mainly exert the analgesic and antipyretic effects through the
inhibition of prostaglandin synthesis. Muscle relaxation studies through
mouse traction test have demonstrated that the compound Chlorzoxazone
showed a dose-dependent muscle relaxant effect with excellent protective
effect on the strychnine-induced seizures in mice. The existence of
paracetamol in the compound chlorzoxazone tablets can further enhance
the effect of chlorzoxazone. Hot plate analgesic tests have showed the
compound chlorzoxazone has a significant analgesic effect in a
dose-dependent manner. It also has antagonism effect on the painful
writhing of mice caused by antimony potassium tartratie in a good
dose-response relationship. Test results have showed that acetaminophen
and chlorzoxazone analgesic synergy.
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- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.