Chlorogenic Acid NEW
| Price | $50 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Chlorogenic Acid | CAS No.: 327-97-9 |
| Purity: 99.67% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Chlorogenic Acid |
| Description | Chlorogenic acid is a natural phenol found in honeysuckle. Chlorogenic acid has a wide range of biological activities including anti-inflammatory, antioxidant, antitumor, antimicrobial, and neuroprotective. |
| In vitro | METHODS: Human colorectal cancer cells Caco-2 were treated with Chlorogenic acid (50-1000 μM) for 24 h and cell viability was measured by MTT assay. RESULTS: Proliferation of Chlorogenic acid-treated cells was significantly reduced, starting at the lowest tested concentration (50 μM), with an EC50 of 758 ± 19.09 μM.[1] METHODS: Mouse mammary carcinoma cells 4T1 were treated with Chlorogenic acid (50-200 μM) for 24 h to enable detection of apoptosis by Flow cytometry. RESULTS: In the early stage, the level of apoptotic cells (Annexin V+/PI-) increased significantly from 1.14% to 0.04%, 34.56%, 40.9% and 37.46% with increasing concentrations of Chlorogenic acid (0, 50, 100, 150 and 200 μM, respectively). Whereas, in the late phase, when the cells were treated with Chlorogenic acid, the apoptotic cell ratio (Annexin V+/PI+) significantly increased from 2.34% to 2.08%, 13.45%, 17.7% and 29.06%, respectively. [2] |
| In vivo | METHODS: To assess the anti-obesity effects, Chlorogenic acid (150 mg/kg) was administered by gavage to ICR mice on a high-fat diet model (HFD) once daily for six weeks. RESULTS: Administration of Chlorogenic acid significantly promoted weight loss, decreased plasma lipid levels, and altered mRNA expression of genes related to adipogenesis and lipolysis in adipose tissue. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 66 mg/mL (186.3 mM) DMSO : 66 mg/mL (186.3 mM) H2O : 10 mg/mL |
| Keywords | Reactive Oxygen Species | NSC407296 | NSC 407296 | Inhibitor | inhibit | Influenza Virus | Hypoxia-inducible factors | HIFs | HIF-PH | HIF/HIF Prolyl-Hydroxylase | Endogenous Metabolite | Chlorogenic Acid | Bacterial |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Tobacco Monomer Library | Neuroprotective Compound Library | Microbial Natural Product Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-infective Natural Product Library | Ancient Chinese Classical Formulas Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1.00/1KG |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-13 | |
| $11.00/1ASSAYS |
VIP4Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-21 | |
| $6.00/1kg |
VIP1Y
|
HebeiShuoshengImportandExportco.,Ltd
|
2024-08-05 | |
| $7.00/1KG |
VIP1Y
|
Hebei Longbang Technology Co., Ltd
|
2024-05-24 | |
| $18.00/10kg |
VIP1Y
|
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
|
2024-05-10 | |
| $10.00/1KG |
VIP2Y
|
Henan Fengda Chemical Co., Ltd
|
2024-04-28 | |
| $6.00/1KG |
VIP1Y
|
Hebei Saisier Technology Co., LTD
|
2024-04-25 | |
| $15.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-04-23 | |
| $480.00/100g |
VIP1Y
|
R&D Scientific Inc.
|
2024-03-31 | |
| $0.00/1kg |
VIP1Y
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
2024-03-28 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY