Chitosan (MW 150000) NEW
| Price | $42 |
| Package | 1g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: Chitosan (MW 150000) | CAS No.: 9012-76-4 |
| Supply Ability: 10g | Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | Chitosan (MW 150000) |
| 描述 | Chitosan (MW 150000) (Deacetylated chitin) is a linear polysaccharide made up of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine. |
| 體外活性 | Chitosans are recognized as versatile biomaterials because of their non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan is reported to have other biological properties, such as antitumor, antimicrobial, and antioxidant activities. It can be used in water treatment, wound-healing materials, pharmaceutical excipient or drug carrier, obesity treatment and as a scaffold for tissue engineering[1]. Antimicrobial activity of chitosan has been demonstrated against many bacteria, filamentous fungi and yeasts. Chitosan has wide spectrum of activity and high killing rate against Gram-positive and Gram-negative bacteria, but lower toxicity toward mammalian cells[2]. Chitosan exhibits antitumor activity against different types of cancer. For example, chitosan decreases adhesion of primary melanoma A375 cell line and decreases proliferation of primary melanoma SKMEL28 cell line, it has potent pro-apoptotic effects against RPMI7951, a metastatic melanoma cell line[3]. Chitosan and its derivatives act as antioxidants by scavenging oxygen radicals such as hydroxyl, superoxide, alkyl as well as highly stable DPPH radicals in vitro[4]. |
| 體內(nèi)活性 | Chitosan treatment dramatically increases lifespan and inhibits tumor metastasis especially in treatment groups of the low-molecular weight compound[5]. Chitosan has some apparent treatment effects on rat PCP by reducing HSP70 mRNA expression and lung inflammation, increasing the concentrations of IL-10 and IFN-γ as well as CD4(+) T-lymphocyte numbers, reducing the CD8(+) T-lymphocyte numbers and the concentration of TNF-α and inducing significant ultrastructural damage to P. carinii[6]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : Slightly soluble |
| 關(guān)鍵字 | Chitosan (MW 150000) |
| 相關(guān)產(chǎn)品 | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Doxycycline | Geraniol | Dimethyl sulfoxide |
| 相關(guān)庫 | 人內(nèi)源代謝化合物庫 Plus |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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