Chelidonine hydrochloride NEW
Price | $78 | $183 | $668 |
Package | 1mg | 5mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Chelidonine hydrochloride | CAS No.: 4312-31-6 |
Purity: 100% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Chelidonine hydrochloride |
描述 | Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities |
體外活性 | Chelidonine significantly suppressed LPS-induced the production of NO and PGE2, as well as iNOS and COX-2 mRNA and protein expression.?In addition, pro-inflammatory cytokines induced by LPS, such as TNFα and IL-6 were also attenuated by chelidonine.?What's more, LPS-induced activation and degradation of IκBα followed by translocation of the p65 from the cytoplasm to the nucleus were attenuated by chelidonine.?Furthermore, chelidonine even significantly inhibited TLR4 expression induced by LPS[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : <10 mM |
關(guān)鍵字 | Chelidonine Hydrochloride | Chelidonine hydrochloride |
相關(guān)庫 | 經(jīng)典已知活性庫 | 生物堿類天然產(chǎn)物庫 | 稀有天然產(chǎn)物庫 | 中國藥典收錄天然產(chǎn)物庫 | NO PAINS 化合物庫 | 高通量篩選天然產(chǎn)物庫 | Ro5類藥天然產(chǎn)物庫 | 已知活性化合物庫 | 蒙藥化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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