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Postion:Product Catalog >Cenerimod
Cenerimod
  • Cenerimod

Cenerimod NEW

Price $35 $56 $95
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: Cenerimod CAS No.: 1262414-04-9
Purity: 97.43% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱Cenerimod
描述Cenerimod (ACT-334441) is an orally active, selective, and potent sphingosine 1-phosphate receptor (S1P1) agonist (EC50: 1 nM).Cenerimod inhibits multiple S1P isoforms and can be used to study murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma.
體外活性Cultured fibroblasts were pretreated with a vehicle or Cenerimod (5 μmol/L), followed by incubation with TGF-β2 (10 ng/mL) for 24 hours. The results indicated that Cenerimod inhibited collagen production in fibroblasts[1].
體內(nèi)活性In male Wistar rats weighing 294-510 g, Cenerimod (0.1, 0.3, 1, 3, and 10 mg/kg; single oral dose) effectively and reversibly reduced blood lymphocyte counts[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 80 mg/mL (176.39 mM), Sonification is recommended.
關(guān)鍵字ACT 334441 | Cenerimod | ACT334441
相關(guān)產(chǎn)品Fingolimod hydrochloride | SLP9101555 | SKI-178 | LX-2931 | K145 hydrochloride | ASP-4058 | Ceranib-2 | Siponimod | MP-A08 | Ozanimod
相關(guān)庫經(jīng)典已知活性庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$35.00/2mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-18
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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