Carbimazole NEW
| Price | $46 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Carbimazole | CAS No.: 22232-54-8 |
| Purity: 99.22% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Carbimazole |
| 描述 | Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease. |
| 激酶實驗 | In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. Total and phosphorylated S6 at ser235/236 and ser240/244 are detected by western analysis using phosphospecific antibodies. Note that recombinant GST-tagged S6 (53 kd) is distinguished from endogenous S6 (32 kd) on the western blot. |
| 體內(nèi)活性 | Once absorbed by the human body, Carbimazole is metabolized into Methimazole, which exerts anti-thyroid activity. It specifically targets conditions such as hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (thyroid inflammation). |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 12 mg/mL (64.4 mM) DMSO : 60 mg/mL (322.18 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| 關(guān)鍵字 | Carbimazole | antithyroid agent | MMI | inhibit | Graves' disease | Inhibitor | methimazole |
| 相關(guān)產(chǎn)品 | Propylthiouracil | Liothyronine | L-Thyroxine | L-Thyroxine sodium | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Resmetirom | Methimazole | Liothyronine sodium | 2-Thiouracil | Tiratricol |
| 相關(guān)庫 | 核受體化合物庫 | 經(jīng)典已知活性庫 | 兒童藥物庫 | ReFRAME 相關(guān)化合物庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 內(nèi)分泌激素分子庫 | 已知活性化合物庫 | 抗代謝疾病化合物庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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