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Postion:Product Catalog >Carabersat
Carabersat
  • Carabersat

Carabersat NEW

Price $700 $1800
Package 1mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: Carabersat CAS No.: 184653-84-7
Purity: 100% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameCarabersat
DescriptionCarabersat(SB 204269) is a novel and effective anticonvulsant and antiepileptic agent.
In vitro[3H]Carabersat ([3H]SB 204269) binds to rat forebrain membranes with moderate affinity (Kd 40 nM) and pKi values of 7.3[1]. In mouse forebrain membranes, Carabersat is able to bind, and the binding is saturable and stereospecific, with a Kd of 53 nM. The labeled [3H]Carabersat produces a Kd of 32 nM[2]. Carabersat (SB-204269, 1-100 μM) has no effect on Na+ current in cultured hippocampal neurons. It also shows no effect on action potential discharges evoked by elevating external K+[4]. Structurally related to the benzopyran ATP-sensitive potassium channel (KATP) opener cromakalim, Carabersat (SB-204269) has opposite stereochemistry, and its mechanism of action is not thought to involve KATP[3].
In vivoSignificantly elevating anticonvulsant activity in mice, Carabersat (5b) has been observed[1].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsCarabersat

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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