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Postion:Product Catalog >API>Vitamins and Minerals medicines>Vitamins AD drugs>Calcifediol
Calcifediol
  • Calcifediol

Calcifediol NEW

Price $44 $97 $155
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: Calcifediol CAS No.: 19356-17-3
Purity: 99.28% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱Calcifediol
描述Calcifediol (U 32070E) is a naturally occurring product that is metabolized in the liver from vitamin D3, a VDR ligand. Calcifediol is indicated for use as a vitamin supplement for all patients with vitamin D deficiency.
體外活性Calcifediol, whether in liposomes or ethanolic solution, does not affect the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. However, treating infected human bronchial 16-HBE cells with Calcifediol liposomes significantly reduces bacterial survival [1].
體內(nèi)活性METHODS: Calcifediol (25 μg/kg) was administered dietary to rats for four weeks to study its role in pregnancy. RESULTS: Calcifediol provided better vitamin D availability to the mother and fetus when administered during pregnancy compared to vitamin D3. No adverse effects on pregnancy outcome were observed, and further studies are needed to investigate the effects of Calcifediol on fetal brain VDR and GAD67 expression. [3]
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 18.33 mg/mL (45.76 mM)
Ethanol : 16 mg/mL (39.9 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
關(guān)鍵字Calcifediol | Vitamin D receptor | VD/VDR | Vitamin D | Inhibitor | inhibit | Endogenous Metabolite
相關(guān)產(chǎn)品Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Vanillin | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid | Oleic acid
相關(guān)庫(kù)經(jīng)典已知活性庫(kù) | 天然產(chǎn)物庫(kù) | 抑制劑庫(kù) | FDA 上市藥物庫(kù) | 高通量篩選天然產(chǎn)物庫(kù) | 人內(nèi)源代謝化合物庫(kù) | 已知活性化合物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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