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Postion:Product Catalog >API>Nervous system drugs>Anxiolytics>Buspirone hydrochloride
Buspirone hydrochloride
  • Buspirone hydrochloride

Buspirone hydrochloride NEW

Price $50
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-01

Product Details

Product Name: Buspirone hydrochloride CAS No.: 33386-08-2
Purity: 99.95% Supply Ability: 10g
Release date: 2025/05/01

Product Introduction

Bioactivity

NameBuspirone hydrochloride
DescriptionBuspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
In vitroBuspirone, a clinically effective non-benzodiazepine anxiolytic drug, causes inhibition of firing of these neurons when given by intravenous (ED50 = 0.011 mg/kg, i.v.), intraperitoneal (ED50 = 0.088 mg/kg, i.p.), and intragastric (effective dose = 1.0-20.0 mg/kg, i.g.) injection. Buspirone also inhibits these cells when it is administered to the outside of recorded neurons by microiontophoresis. [1] Buspirone is eliminated primarily by oxidative metabolism, which produces several hydroxylated metabolites, including 5-hydroxy-buspirone and 1-pyrimidinylpiperazine. [2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 42.2 mg/mL (100.01 mM), Sonication is recommended.
DMSO : 50 mg/mL (118.49 mM), Sonication is recommended.
KeywordsSerotonin Receptor | Reactive Oxygen Species | Inhibitor | inhibit | DopamineReceptor | Dopamine Receptor | Dopamine | depression | Buspirone hydrochloride | Buspirone Hydrochloride | Buspirone | anxiety | 5-hydroxytryptamine Receptor | 5HTReceptor | 5-HT1A receptor | 5-HT Receptor | 5HT Receptor | 5-HT
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | Clozapine N-Oxide | Octopamine hydrochloride | D-Menthol | Citicoline | Amitriptyline hydrochloride | Oxolinic acid | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine
Related Compound LibrariesFailed Clinical Trials Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Address: 36 Washington Street, Wellesley Hill, MA
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