Brilliant Black BN NEW
| Price | $48 | $68 | $98 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: Brilliant Black BN | CAS No.: 2519-30-4 |
| Supply Ability: 10g | Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | Brilliant Black BN |
| 描述 | Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. |
| 體外活性 | Brilliant black BN inhibited the infection EV71 -GFP at a concentration of 300 μM. Brilliant black BN exhibits the inhibition of EV71 -GFP as a dose-dependent manner in infected RD cells (IC50: 10.1 μM). Brilliant black BN is able to inhibit all tested 28 EV71, CVA16, and CVA6 strains. In rhabdomyosarcoma cells, 50% inhibitory concentration 29 of the dye E151 for various strains of EV71 ranged from 2.39 μM to 28.12 μM, whereas its 50% cytotoxic concentration is 1870 μM [2]. |
| 體內(nèi)活性 | Brilliant black BN (i.p.; 200 mg/kg; 14 days)exhibits mild illness with clinical scores less than 3 and subsequently recovered when compared with PBS-group. All E151 270 treated mice are completely protected throughout the experiment [2]. |
| 存儲(chǔ)條件 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 123 mg/mL (141.75 mM), Sonication is recommended. |
| 關(guān)鍵字 | HFMD | HEVs | additive,contagious | HEV | EV71,infection | HRVs | antiviral,food | HRV | Rhinovirus | Enterovirus | E-151 | Brilliant Black BN | inhibit | E151 | Inhibitor | disease |
| 相關(guān)產(chǎn)品 | Phenytoin sodium | Anthraquinone | 2-Phenylethanol | 4-Phenylbutyric acid |
| 相關(guān)庫 | 化妝品成分化合物庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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