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    Postion:Product Catalog >BQR-695
    BQR-695
    • BQR-695

    BQR-695 NEW

    Price $64 $89 $197
    Package 5mg 10mg 25mg
    Min. Order:
    Supply Ability: 10g
    Update Time: 2024-11-19

    Product Details

    Product Name: BQR-695 CAS No.: 1513879-21-4
    Purity: 97.16% Supply Ability: 10g
    Release date: 2024/11/19

    Product Introduction

    Bioactivity

    NameBQR-695
    DescriptionBQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.
    In vitroBQR695 demonstrates no toxicity towards mature red blood cells (RBCs), triggers a schizont-stage halt akin to the effects seen in imidazopyrazine-treated parasites, and shows cross-resistance with imidazopyrazine-resistant strains. Administering 0.5 μM of KAI407 or BQR695 leads to the redistribution of GFP-PHOsh2 to the parasite's plasma membrane, indicating a decrease in intracellular PI4P due to the inhibition of PfPI4K activity.
    StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
    Solubility InformationDMSO : 50 mg/mL (141.89 mM)
    KeywordsPI4K | PI4 kinases | Parasite | NVP-BQR-695 | BQR 695 | BQR-695 | Inhibitor | inhibit | Phosphatidylinositol 4 kinases | NVP-BQR 695
    Inhibitors RelatedPicaridin | Kaempferol | Myricetin | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | Benzyl benzoate | DL-Methionine
    Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Reprogramming Compound Library | Glycolysis Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Antioxidant Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

    Company Profile Introduction

    Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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