BMS CCR2 22 NEW
Price | $53 | $118 | $193 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: BMS CCR2 22 | CAS No.: 445479-97-0 |
Purity: 99.05% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱(chēng) | BMS CCR2 22 |
描述 | BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM. |
體外活性 | BMS CCR2 22 inhibits the internalization of hMCP1_AF647 (IC50 = 2 nM)[2]. HAoECs with BMS CCR2 22 before MCP-1 increases the cell surface levels of VCAM-1 from 72.8 to 160% and PECAM1 from 97.2 and 127%[3]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 225.0 mg/mL (379.0 mM), Sonication is recommended. |
關(guān)鍵字 | BMS CCR-2 22 | BMS CCR2 22 |
相關(guān)產(chǎn)品 | Aplaviroc | AZD2098 | MLN-3897 TFA | CCR2 antagonist 5 | INCB-9471 | CCR3 antagonist 1 | BMS-817399 | PF-4136309 | C-021 | Pirfenidone | Vercirnon | CCR6 antagonist 1 |
相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 細(xì)胞因子抑制劑庫(kù) | 膜蛋白靶向化合物庫(kù) | 抑制劑庫(kù) | 腫瘤免疫治療小分子化合物庫(kù) | 免疫/炎癥分子化合物庫(kù) | 已知活性化合物庫(kù) | 共價(jià)抑制劑庫(kù) | 含氟化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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