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Postion:Product Catalog >BMS-986165
BMS-986165
  • BMS-986165

BMS-986165

Price Get Latest Price
Package 1kg 10kg 1000kg
Min. Order: 25kg
Supply Ability: 20tons
Update Time: 2023-07-25

Product Details

Product Name: BMS-986165 CAS No.: 1609392-27-9
Min. Order: 25kg Purity: 99.5%
Supply Ability: 20tons Release date: 2023/07/25

Chinese name: BMS-986165

Chinese synonym: compound BMS-986165; BMS-986165; BMS986165; BMS986165; DEUCRAVACITINIB

English name: BMS-986,165

English synonym: BMS-986165; Tyk2-IN-4; TYK2-IN-4; BMS986165; BMS-986165; BMS986165; 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide; Deucravacitinib; Deucravacitinib(BMS986165); Deucravacitinib(TYK2-IN-4;6-cyclopropaneamido-4-{[2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]amino}-N-(2H?)methylpyridazine-3-carboxamide

CAS No.: 1609392-27-9

Molecular formula: C20H22N8O3

Molecular weight: 422.45EINECS No.:

Related categories: new products; Inhibitors; Pharmaceutical and chemical raw materials; Fine chemical products; Standards; Pharmaceutical raw materials; Belka; API; APIS; APIMol file: 1609392-27-9.molBMS-986165 Property: BMS-986165

Application and synthesis method

Purposes BMS-986,165 is a new type of oral selective TYK2 inhibitor. Its unique mechanism of action is expected to provide a promising oral choice to help patients effectively control their psoriasis.

The bioactive Deucravacitinib (BMS-986165) is a powerful and selective allosteric inhibitor of Tyk2. The Ki value of its binding to the pseudo kinase domain of Tyk2 is 0.02 nM. It is highly selective for a group of 265 kinases and pseudokinases. TargetValueTyk2 (Cell freeassay) 0.02nM


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