• DATA ITEMS CITED :

• 8

• MOLECULAR FORMULA :

• C33-H36-N4-O6

• MOLECULAR WEIGHT :

• 584.73

• WISWESSER LINE NOTATION :

• T5VMYTJ D1 E1U1 CU1- ET5MYTJ C2VQ D1 BU1- ET5MYTJ C1 D2VQ BU1- ET5MVTJ C1 D1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Oral

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• >15 gm/kg

• TOXIC EFFECTS :

• Behavioral - somnolence (general depressed activity)

• REFERENCE :

• ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (103),29,1985

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Intraperitoneal

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• >2 gm/kg

• TOXIC EFFECTS :

• Gastrointestinal - other changes

• REFERENCE :

• ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (103),29,1985 ** REPRODUCTIVE DATA **

• TYPE OF TEST :

• TDLo - Lowest published toxic dose

• ROUTE OF EXPOSURE :

• Intraperitoneal

• DOSE :

• 175 mg/kg

• SEX/DURATION :

• female 9-15 day(s) after conception

• TOXIC EFFECTS :

• Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

• REFERENCE :

• AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 127,497,1977

• TYPE OF TEST :

• TDLo - Lowest published toxic dose

• ROUTE OF EXPOSURE :

• Intraperitoneal

• DOSE :

• 25 mg/kg

• SEX/DURATION :

• female 12 day(s) after conception

• TOXIC EFFECTS :

• Reproductive - Effects on Embryo or Fetus - other effects to embryo

• REFERENCE :

• AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 127,497,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81726 No. of Facilities: 114 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1390 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81726 No. of Facilities: 1176 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 12638 (estimated) No. of Female Employees: 9389 (estimated)