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Postion:Product Catalog >API>Circulatory system drugs>Peripheral vasodilators>Betahistine dihydrochloride
Betahistine dihydrochloride
  • Betahistine dihydrochloride

Betahistine dihydrochloride NEW

Price $29
Package 1mL
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-28

Product Details

Product Name: Betahistine dihydrochloride CAS No.: 5579-84-0
Purity: 99.88% Supply Ability: 10g
Release date: 2025/04/28

Product Introduction

Bioactivity

NameBetahistine dihydrochloride
DescriptionBetahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.
In vitroIn mice, Betahistine (ED50=2 mg/kg) elevates t-MeHA levels in a dose-dependent manner. In patients with Ménière's disease, Betahistine (16 mg, twice daily for 3 months) significantly alleviates vertigo. Additionally, Betahistine (50 mg/kg) induces an upregulation of histidine decarboxylase mRNA in the nodose ganglion of the cat brain.
In vivoIn CHO(H3R) cells treated with 3 μM of, Betahistine progressively increased cAMP formation, peaking at 10 nM. Furthermore, in CHO(H3R) cells, Betahistine progressively reduced A23187-induced [3H]arachidonic acid release (EC50=0.1 nM), with the greatest effect observed at 30 nM.
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (239.1 mM), Sonication is recommended.
H2O : 35 mg/mL (167.37 mM), Sonication is recommended.
Ethanol : 1 mg/mL (4.78 mM), Sonication is recommended.
Keywordsschizophrenia | Rheumatoid | PT9 | PT 9 | Ménière | Inhibitor | inhibit | HistamineReceptor | Histamine Receptor | H3 receptor | episode | disease | CIA | Betahistine dihydrochloride | Betahistine Dihydrochloride | Betahistine | arthritis | antipsychotic
Inhibitors RelatedChlorphenesin | Histamine dihydrochloride | Meclizine dihydrochloride | Mirtazapine | Lidocaine | Famotidine | Mebhydrolin napadisylate | Sodium butanoate | Amitriptyline hydrochloride | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride
Related Compound LibrariesFailed Clinical Trials Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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