beta-Amyrone NEW
Price | $122 | $372 | $597 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: beta-Amyrone | CAS No.: 638-97-1 |
Purity: 99.55% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | beta-Amyrone |
Description | beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity. |
In vitro | beta-Amyrone inhibits α-glucosidase AChE and fungal activity with IC50 values of 25 μM, 23 μM and 8 μg/mL, respectively[1]. In LPS-stimulated J774 cells, beta-Amyrone (2.5, 5, 10 μg/mL) inhibits NO production with an IC50 value of 4.61 μg/mL without obvious effects on cell viability[4]. beta-Amyrone (10 μg/mL) inhibits IL-6, IL-10 levels, and COX-2 expression at the dose of 10 μg/mL[4]. |
In vivo | In ear phenol-induced edema in Balb C mice, beta-Amyrone (0.1, 0.3, 0.6 mg/kg) inhibits ear edema formation in a dose-related manner[4]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : Insoluble |
Keywords | antifungal | AChE | COX-2 | PI3K-Akt | Anti-inflammatory | Fungal | inflammation | beta-Amyron | β-Amyrone | CHIKV | Cyclooxygenase | b-Amyron | inhibit | Inhibitor | infection | beta-Amyrone | obesity | Peroxisome proliferator-activated receptors | COX | b-Amyrone | PPAR |
Inhibitors Related | Bismuth Subsalicylate | Ibuprofen | Acetaminophen | Daidzein | Metronidazole | L-Lysine | Diclofenac sodium | Diclofenac Potassium | Naringenin | Paradol | Salicylic acid | 2,3-Butanediol |
Related Compound Libraries | Anti-Tumor Natural Product Library | Terpene Natural Product Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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