Product Details
Product Name:
BCH001 |
CAS No.:
384859-58-9 |
Purity:
99.06% |
Supply Ability:
10g |
Release date:
2024/11/18 |
Product Introduction
Bioactivity
名稱 | BCH001 |
描述 | BCH001 is a specific small-molecule inhibitor of PAPD5. |
體內(nèi)活性 | BCH001, a specific PAPD5 inhibitor that restored telomerase activity and telomere length in DC patient induced pluripotent stem cells.?When human blood stem cells engineered to carry DC-causing PARN mutations were xenotransplanted into immunodeficient mice, oral treatment with a repurposed PAPD5 inhibitor, the dihydroquinolizinone RG7834, rescued TERC 3' end maturation and telomere length.? |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 84 mg/mL (199.84 mM)
|
關(guān)鍵字 | PARN | dyskeratosis | telomerase | stem | polynucleotide | TERC | rPAPD5 | ncRNA | BCH-001 | polymerases | oligo-adenylation | congenita | inhibit | PAPD5 | pluripotent | BCH 001 | iPSC | DNA/RNA Synthesis | BCH001 | telomere | Inhibitor |
相關(guān)產(chǎn)品 | Rifampicin | 5-Fluorouracil | Ribavirin | Guanidine hydrochloride | 2,4-D | Resveratrol | Trimethoprim | Azelaic acid | Acyclovir | Thymidine | Temozolomide | Folic acid |
相關(guān)庫 | DNA 損傷和修復分子庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | NO PAINS 化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 細胞周期化合物庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |