Product Name:    Baclofen

Synonyms:    4-Amino-3-(p-chlorophenyl)butyric acid;Benzenepropanoic acid, β-(aminomethyl)-4-chloro-;CIBA Ba 34647;DL-4-Amino-3-p-chlorophenylbutanoic acid;DL-Baclofen;Hydrocinnamic acid, β-(aminomethyl)-p-chloro- (7CI, 8CI);β-(4-Chlorophenyl)-γ-aminobutyric acid;β-p-Chlorophenyl-GABA

CAS:    1134-47-0

MF:    C10H12ClNO2

MW:    213.66

EINECS:    214-486-9

Product Categories:    KEMSTRO;GABA;Intermediates & Fine Chemicals;GABA/Glycine receptor;Amines;Aromatics;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Active Pharmaceutical Ingredients;Pharmaceuticals;Used as a skeletal muscle relaxation of the spinal cord, sedatives;API;Piperazines ,Oxazolines/Oxazolidines;1134-47-0

Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord. Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s.