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Postion:Product Catalog >API>Antibiotics>Penicillins drugs>Azlocillin sodium salt
Azlocillin sodium salt
  • Azlocillin sodium salt

Azlocillin sodium salt NEW

Price $30 $48
Package 200mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: Azlocillin sodium salt CAS No.: 37091-65-9
Purity: 97.63% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱Azlocillin sodium salt
描述Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics
體外活性Azlocillin (12.5 μg/mL) inhibits over 75% of the isolates of Pseudomonas aeruginosa. Azlocillin (12.5 μg/mL) is also active against indole-negative and -positive Proteus spp., inhibiting 98 and 71%, respectively. Azlocillin is more active than mezlocillin, ticarcillin, and carbenicillin and as active as BLP-1654 against isolates of P. aeruginosa. [1] The acyl side chains of Azlocillin have an ureido-(urea) structurehence the name 'ureidopenicillins' or, more specifically, 'acylureidopenicillins.' In vitro studies against P. aeruginosa demonstrates that piperacillin has activity that is twice that of azlocillin, 4 times that of mezlocillin and ticarcillin, and about 8 times that of carbenicillin. Azlocillin produces elongated bacterial forms with delayed or no lysis in morphologic studies. [2] Azlocillin has MICs of 12.5 μg/mL on Pseudomonas aeruginosa. Azlocillin (3.125 μg/mL) results in a reduction in the rate of growth but no bactericidal phase on Pseudomonas aeruginosa. Azlocillin decreases an initial lag phase with increasing drug concentration. At the lower concentration of tobramycin (0.5 μg/ml), the combinations with both the high and the low concentrations of Azlocillin are more effective than the individual components on Pseudomonas aeruginosa. [3] Isolates with derepression of AmpC enzyme are one to two doubling dilutions more resistant to azlocillin than are those in which increased efflux or impermeability is inferred. Those with secondary β-lactamases are mostly (12/14 cases) susceptible to ceftazidime at 4 mg/L, but are amongst the most resistant to Azlocillin (MIC ≥128 mg/L in 10/14 cases). [4]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 90 mg/mL (186.2 mM)
H2O : 89 mg/mL (184.1 mM)
Ethanol : 3 mg/mL (6.19 mM)
關(guān)鍵字piperacillin | Inhibitor | Parasite | penicillin | Azlocillin | Azlocillin sodium salt | Bacterial | inhibit | similar | Antibiotic | mezlocillin
相關(guān)產(chǎn)品Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Hydroxychloroquine | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet
相關(guān)庫FDA上市及藥典收錄分子庫 | 抗寄生蟲庫 | 經(jīng)典已知活性庫 | 抗生素庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 抗菌活性庫 | FDA 上市藥物庫 | 已知活性化合物庫 | 臨床前化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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