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Postion:Product Catalog >AZ31
AZ31
  • AZ31

AZ31 NEW

Price $45 $106 $172
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AZ31 CAS No.: 2088113-98-6
Purity: 98.01% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAZ31
DescriptionAZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
In vitroAZ31 (0.3-3 μM ; 1 h) modulates the phosphorylation of a range of ATM targets.[2] AZ31 (10 μM ; 1 h) influences the stabilization of p53 in H2228 lung cancer cells post-radiation.[2]
In vivoAZ31 (50-100 mg/kg ; p.o. twice daily) exhibits limited penetration into the brain.[2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (59.45 mM)
KeywordsAZ31
Inhibitors RelatedCP-466722 | Ro 90-7501 | Dactolisib | Berzosertib | Elimusertib | GJ103 sodium salt | KU60019 | Ceralasertib | (Z)-Mirin | NU6027 | Schisandrin B | AZ32
Related Compound LibrariesHighly Selective Inhibitor Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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