成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >AZ-23
AZ-23
  • AZ-23

AZ-23 NEW

Price $99
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-08

Product Details

Product Name: AZ-23 CAS No.: 915720-21-7
Purity: 99.4% Supply Ability: 10g
Release date: 2024/11/08

Product Introduction

Bioactivity

名稱AZ-23
描述AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.
體外活性AZ-23 selectively and potently inhibits Trk phosphorylation in cells, with an EC50 of 2 nM for Trk-mediated survival. It also inhibits Trk-dependent survival in MCF10ATrkA-Δ and TF-1 cell lines[1].
體內(nèi)活性Following oral administration in a TrkA-driven allograft model, AZ-23 demonstrates effective in vivo inhibition of TrkA kinase and efficacy in mice. It also significantly inhibits tumor growth in a Trk-expressing xenograft model of neuroblastoma[1].
存儲條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 125 mg/mL (319.02 mM), Sonication is recommended.
關(guān)鍵字AZ-23 | Tropomyosin related kinase receptor | Inhibitor | inhibit | Trk Receptor
相關(guān)產(chǎn)品LM22A-4 | Larotrectinib sulfate | N-Acetyl-5-hydroxytryptamine | Selitrectinib | Sitravatinib | SP600125 | Amitriptyline hydrochloride | 7,8-Dihydroxyflavone | Diosmetin | GW 441756 | CG 428 | ALE-0540

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$2380.00/50mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-23
$695.00/10mg
VIP5Y
TargetMol Chemicals Inc.
2024-10-23
$1.00/1KG
VIP5Y
Career Henan Chemica Co
2020-10-29
$99.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-07
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY