Aurantiamide acetate NEW
| Price | $123 | $263 | $393 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Aurantiamide acetate | CAS No.: 56121-42-7 |
| Purity: 99.68% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Aurantiamide acetate |
| 描述 | Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2]. |
| 體外活性 | Aurantiamide acetate decreases viability of U87 and U251 cancer cells in vitro when used at concentrations ranging from 10 to 100 μM. Aurantiamide acetate inhibited cysteine proteinases, in particular, cathepsin L and B with IC50 of 12 microM and 49 microM, respectively. |
| 體內(nèi)活性 | Aurantiamide acetate reduces tumor growth when administered at a dose of 1 mg via intratumoral injection in a U87 mouse xenograft model. In the adjuvant-arthritic rat model, subcutaneously administered 10 mg/kg body weight of this compound suppressed hind paw swelling. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 55 mg/mL (123.73 mM) |
| 關(guān)鍵字 | Aurantiamide acetate | Inhibitor | cathepsin L | Piper aurantiacum | Aurantiamide Acetate | adjuvant-arthritic | Cathepsin | inhibit | Aurantiamide | inflammatory diseases |
| 相關(guān)產(chǎn)品 | Papain | 2-Aminoethanethiol | (S)-(+)-Ibuprofen | PMSF | KGP94 | N-Ethylmaleimide | Z-Lys-OH | 2-Cyanopyrimidine | Leupeptin Hemisulfate | Esomeprazole | Aloxistatin | E-64 |
| 相關(guān)庫(kù) | 海洋天然產(chǎn)物庫(kù) | 經(jīng)典已知活性庫(kù) | 中藥單體化合物庫(kù) | 煙草單體化合物庫(kù) | 抑制劑庫(kù) | 高通量篩選天然產(chǎn)物庫(kù) | 古代經(jīng)典名方目錄分子庫(kù) | 藥食同源庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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