Description of Artesunate from Wuhan Fortuna Chemical Co.,Ltd

Specifications(COA) of Factory Supply Artesunate CAS 88495-63-0 Active Pharmaceutical Ingredient API for Malaria Treatment

Introduction of Artesunate.

Artesunate is a medication used to treat malaria, a disease caused by parasites that enter the body through the bite of a mosquito. It is a derivative of artemisinin, which is extracted from the sweet wormwood plant (Artemisia annua). Artesunate is particularly effective against Plasmodium falciparum, the most dangerous and deadly species of the malaria parasite.

Artesunate can be administered in various forms, including oral tablets, rectal capsules, and injectable solutions. The injectable form is often used in severe cases of malaria because it acts quickly to reduce the number of parasites in the blood.

The drug works by producing free radicals that damage the parasite’s proteins and cell membranes, leading to its death. Artesunate is often used in combination with other antimalarial drugs to improve efficacy and reduce the risk of resistance developing.

It’s important to note that while artesunate is highly effective, it should be used under medical supervision, and the full course of treatment should be completed to ensure the infection is fully cleared.

Applicaton of Artesunate

Artesunate is primarily used for the treatment of malaria, particularly severe cases caused by Plasmodium falciparum, the most dangerous and drug-resistant species of the malaria parasite.  Here are some specific applications of artesunate:

Severe Malaria Treatment: Artesunate is the first-line treatment for severe malaria.  It is often administered intravenously or intramuscularly in hospital settings to rapidly reduce the parasite load in the blood.

Uncomplicated Malaria: Artesunate can also be used to treat uncomplicated malaria, usually in combination with other antimalarial drugs such as mefloquine, amodiaquine, or lumefantrine.  This combination therapy helps to prevent the development of drug resistance.

Malaria in Pregnancy: Artesunate is considered safe for use in the second and third trimesters of pregnancy and is often recommended for treating severe malaria in pregnant women.  However, its use in the first trimester is generally avoided unless no other effective treatment is available, due to limited safety data.

Rectal Administration: In situations where intravenous or intramuscular administration is not feasible, such as in remote areas, rectal artesunate can be used as a pre-referral treatment to stabilize patients until they can reach a healthcare facility.

Combination Therapy: Artesunate is often used in combination with other antimalarial drugs (Artemisinin-based Combination Therapies or ACTs) to enhance efficacy and reduce the likelihood of resistance.  Common combinations include artesunate-amodiaquine, artesunate-mefloquine, and artesunate-lumefantrine.

Prophylaxis in Special Cases: While not commonly used for prophylaxis, artesunate may be considered in certain high-risk situations or for individuals who cannot tolerate other prophylactic medications.

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is  the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Artesunate with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Artesunate.