Argireline NEW
| Price | $48 | $58 | $67 |
| Package | 5mg | 10mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Argireline | CAS No.: 616204-22-9 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Argireline |
| Description | Argireline (Acetyl hexapeptide-3) is a peptide composed of amino acid chains that significantly inhibits Ca2+-dependent neurotransmitter (acetylcholine) release at the neuromuscular junction, exhibiting notable anti-wrinkle and anti-aging activity[1][2][3]. |
| In vitro | The incubation of Argireline solution in varying concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM) for 48 hours exhibits a dose-dependent antiproliferative effect. The solution also shows similar effects on HSF cells. Argireline in low concentrations does not affect cell proliferation [2]. |
| In vivo | Argireline was administered topically to elderly mice twice daily for six weeks, resulting in notable histological improvements in skin tissue. Specifically, the quantity of type I collagen fibers increased significantly (P < 0.01), and the amount of type III collagen fibers decreased (P < 0.05). This demonstrates Argireline's capability to enhance the histological architecture of skin tissue and restore aged skin[3]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mM |
| Keywords | skin-permeable | BoNTs | inhibit | neurotransmitter | Inhibitor | peptide | Acetyl hexapeptide 3 | non-toxic | Antiwrinkle | anti-aging | short-chain | Argireline | Acetyl hexapeptide3 |
| Related Compound Libraries | Bioactive Compound Library | Drug Repurposing Compound Library | Peptide Compound Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Anti-Aging Compound Library | Clinical Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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