Apelin-12 acetate NEW
Price | $228 | $320 | $497 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Apelin-12 acetate | Purity: 98.82% |
Supply Ability: 10g | Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Apelin-12 acetate |
描述 | Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons. |
體內(nèi)活性 | Apelin-12 acetate significantly improves the neurobehavioral score of the mice with ischemia-reperfusion injury and alleviates brain edema and damage to neurons. Apelin-12 acetate inhibits the morphological changes and apoptosis of neuronal cells in the ischemic penumbra of mice. Apelin-12 acetate downregulates the expression of Bax and caspase-3, inhibits the activity of caspase-3, and upregulates the expression of Bcl-2, an anti-apoptotic protein[2]. |
存儲(chǔ)條件 | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 22.5 mg/mL (15.17 mM) |
關(guān)鍵字 | Apelin-12 Acetate | 229961-08-4 | 229961-08-4 Free base |
相關(guān)產(chǎn)品 | Astragaloside IV | SB 202190 | Anisomycin |
相關(guān)庫 | 抗結(jié)直腸癌化合物庫 | 經(jīng)典已知活性庫 | 疼痛相關(guān)化合物庫 | 膜蛋白靶向化合物庫 | 多肽分子庫 | 抗衰老化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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