Antibacterial agent 141 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Antibacterial agent 141 | CAS No.: 2930013-56-0 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Antibacterial agent 141 |
| Description | Compound B14 (Antibacterial agent 141) exhibits antibacterial activity against the plant pathogens Xoo, Xac, Psa, and Cmm, with an EC50 value of 1.28 μM. It functions by inhibiting cell membrane formation and altering cell permeability. |
| In vitro | Antibacterial agent 141 significantly induces cell membrane rupture in Xoo bacteria [1]. It increases membrane permeability in a concentration-dependent manner within Xoo bacteria [1], and disrupts the surface of the bacterial cell membrane [1]. At concentrations of 3.2 and 6.4 μM, the agent notably reduces the expression of ACC, ACP, and Fab family genes in Xoo bacteria [1]. Additionally, it significantly inhibits biofilm formation of Xoo with increasing concentrations [1], while exhibiting low cytotoxicity towards HepG2 and HK-2 cells [1]. At concentrations ranging from 0.64 to 5.12 μM over 3 to 30 hours, it markedly suppresses the growth of Xoo bacteria [1]. |
| In vivo | Antibacterial agent 141 at a concentration of 200 μg/mL, administered as a single dose over a period of 7 days, exhibited treatment and preventive activity against bacterial blight of 4.64% and 43.33%, respectively [1]. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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