Antibacterial agent 122 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Antibacterial agent 122 | CAS No.: 109310-99-8 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Antibacterial agent 122 |
| Description | Antibacterial agent 122 (compound 15) is a thiourea derivative used in tuberculosis research, demonstrating low cytotoxicity and anti-mycobacterial activity [1]. |
| In vitro | Antibacterial agent 122 (compound 15) (25-200 μM, 24 h) inhibits M. tuberculosis H37Rv with an MIC50 of 5.9 μM, reduces NO production in LPS-stimulated RAW 264.7 cells with an IC50 of 8.1 μM, scavenges NO with an IC50 of 184.2 μM, and nearly completely inhibits iNOS expression at 100 μM [1]. Additionally, at concentrations of 0-200 μM, it inhibits TNF-α and IL-1β production in LPS-stimulated macrophages with IC50 values of 28.4 μM and 47.9 μM, respectively. Furthermore, at 25-100 μM over 4 days, it inhibits M. tuberculosis M299 with an MIC50 of 24.7 μM [1]. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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