Angiotensin (1-7) acetate NEW
| Price | $30 | $48 | $78 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Angiotensin (1-7) acetate | CAS No.: 2855063-75-9 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Angiotensin (1-7) acetate |
| Description | Angiotensin (1-7) acetate (Ang-(1-7) acetate) is an amino acid sequence present in angiotensin, which has antifibrotic and cardioprotective effects and inhibits the activity of purified canine angiotensin converting enzyme (ACE). Angiotensin (1-7) acetate inhibits the growth of tumor cells and reduces local inflammation and angiogenesis in several types of cancer, blocks angiotensin II-induced smooth muscle cell proliferation and hypertrophy, and can be used to study atherosclerosis and novel coronavirus infection. |
| In vitro | Pretreatment with Angiotensin (1-7) acetate (2 μM) significantly inhibited the degradation of 125I-[Tyr0]-BK as well as the appearance of BK-(1-7) and BK-(1-5) metabolites in the coronary vascular ring; Angiotensin (1-7) acetate inhibited the angiotensin-converting enzyme activity of purified canine angiotensin converting enzyme with an IC50 of 0.65 μM.[2] |
| In vivo | METHODS: Angiotensin (1-7) acetate (0.01-0.06 mg/kg,daily) was used to treat DSS-induced colitis mice, and colonic expression/activity profiles of ACE2, Ang 1-7, MAS1-Receptor (MAS1-R), MAPK family and Akt were determined by western blotting and immunofluorescence. RESULTS: Enhanced colonic expression of ACE2, Ang 1-7, and MAS1-R was observed in mice after Angiotensin (1-7) acetate treatment and significantly ameliorated DSS-induced colitis. [3] |
| Storage | keep away from direct sunlight | store at -20°C | Shipping with blue ice. |
| Solubility Information | H2O : 50 mg/mL（52.13 mM), Sonication is recommended. |
| Keywords | Angiotensin | Angiotensin (1 7) (acetate) | Angiotensin (17) (acetate) |
| Inhibitors Related | Olmesartan Medoxomil | Tranilast | Enalapril Maleate | Azilsartan Methyl Ester | Sacubitril/Valsartan | Azilsartan | Sinapinic Acid | Irbesartan | Losartan | Ramipril | Captopril | Valsartan Methyl Ester |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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