Amodiaquine dihydrochloride dihydrate NEW
| Price | $36 | $50 | $75 |
| Package | 50mg | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Amodiaquine dihydrochloride dihydrate | CAS No.: 6398-98-7 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Amodiaquine dihydrochloride dihydrate |
| Description | Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. |
| Kinase Assay | Whole-cell competitive binding assays: Whole-cell competitive binding assays are performed in LNCaP/AR(codon-switch) (LNCaP/AR(cs)) (harbors a mixture of exogenous wild-type AR and endogenous mutant AR (T877A)) and cells propagated in Iscove's or RPMI media supplemented with 10% fetal bovine serum, or during the assay with 10% charcoal-stripped, dextran-treated fetal bovine serum (CSS). Cells are pre-incubated with 18F-FDHT, increasing concentrations (1pM to 1 μM) of cold Bicalutamide are added, and the assay is performed to measure specific uptake of 18F-FDHT (4). IC50 values are determined using a one site binding model with least squares curve fitting and R2 > 0.99. |
| In vivo | In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs[3]. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 85 mg/mL (182.87 mM), Sonication is recommended. H2O : 27 mg/mL (58.09 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Parasite | Nurr1 | N-methyltransferase | neuroprotective | Inhibitor | inhibit | IL-1β | HistoneMethyltransferase | Histone Methyltransferase | HistamineReceptor | Histamine Receptor | histamine N-methyl transferase | CXCL2 | CCL2 | antimalarial | anti-inflammatory | Amodiaquine Hydrochloride | Amodiaquine dihydrochloride dihydrate | Amodiaquine dihydrochloride Dihydrate | Amodiaquine | Amodiaquin dihydrochloride Dihydrate | Amodiaquin |
| Inhibitors Related | Kaempferol | Kojic acid | Meclizine dihydrochloride | Urethane | Hydroxychloroquine | Famotidine | Metronidazole | Nitazoxanide | Doxycycline | Artemisinin | Sodium butanoate | DL-Methionine |
| Related Compound Libraries | Anti-Parasitic Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Bitter Compound library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $36.00/50mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2025-05-02 | |
| $36.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-04-29 | |
| $10.00/1kg |
Wuhan Xinhao Biotechnology Co., Ltd
|
2024-01-17 | ||
| $1.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-01-08 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY