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Postion:Product Catalog >AM-8123
AM-8123
  • AM-8123

AM-8123 NEW

Price $293 $435 $722
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-16

Product Details

Product Name: AM-8123 CAS No.: 2049973-02-4
Purity: 99.76% Supply Ability: 10g
Release date: 2024/11/16

Product Introduction

Bioactivity

名稱AM-8123
描述AM-8123 is an orally available nonpeptide APJ agonist.AM-8123 reduces collagen load and improves cardiac function. AM-8123 ameliorates myocardial infarction in rats and can be used to study cardiovascular diseases such as heart failure.
體外活性AM-8123 inhibits histamine-stimulated cAMP production and promotes Gα protein activation[1].
體內(nèi)活性In 2-3-month-old Lewis rats, AM-8123 (100 mg/kg; oral administration) resulted in sustained improvement in systolic function. Additionally, echocardiography measurements showed that AM-8123 reduced end-diastolic volume (EDV) and end-systolic volume (ESV); however, no significant changes were observed by invasive pressure-volume conductance catheter measurements at the end of the study[1].
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
關(guān)鍵字AM8123 | AM-8123 | AM 8123
相關(guān)產(chǎn)品ELA-11 (human) acetate(1784687-32-6 free base) | Apelin-12 acetate | Azelaprag | [Pyr1]-Apelin-13 | CMF019

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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