Altretamine NEW
| Price | $30 | $40 | $70 |
| Package | 50mg | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Altretamine | CAS No.: 645-05-6 |
| Purity: 99.84% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Altretamine |
| Description | Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity. |
| In vitro | In elevated plus-maze and light/dark tests in BALB/c mice, Flumazenil (1 mg/kg) exhibited strong anxiolytic effects. Flumazenil (3 mg/kg) prevented alterations induced by chronic ethanol withdrawal in mice, such as decreased open arm time and percentage of open arm entries. In rats, Flumazenil (10 mg/kg) effectively counteracted the reductive effects of tetrahydropregnanolone. Flumazenil (5-20 mg/kg) antagonized the effects of diazepam in mice without affecting the anticonvulsant and adverse responses to GYKI52466. In the MES model, as opposed to the PTZ test, Flumazenil slightly reduced the anticonvulsant activity of NBQX. Flumazenil binds to central benzodiazepine (BZD) receptors, thereby antagonizing or reversing the neurophysiological effects of BZD depressants and agonists. It reverses the depressant sedative responses caused by the combined use of BZD and other drugs but is not effective for cyclic antidepressant overdose. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 8.4 mg/mL (39.95 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 8 mg/mL (38 mM) |
| Keywords | RB 1515 | WR95704 | DNA Alkylator/Crosslinker | Inhibitor | WR 95704 | inhibit | Altretamine | ENT 50852 | RB1515 | NSC 13875 | NSC-13875 | ENT50852 |
| Inhibitors Related | Cyclophosphamide hydrate | Bendamustine hydrochloride | Busulfan | N-Nitroso-N-methylurea | Ifosfamide | Oxaliplatin | Streptozocin | Temozolomide | Methyl methanesulfonate | Cyclophosphamide | Carboplatin | Cisplatin |
| Related Compound Libraries | Bioactive Compound Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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