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Postion:Product Catalog >API>Nervous system drugs>Anxiolytics>alpha,alpha-Diphenyl-4-piperidinemethanol
alpha,alpha-Diphenyl-4-piperidinemethanol
  • alpha,alpha-Diphenyl-4-piperidinemethanol

alpha,alpha-Diphenyl-4-piperidinemethanol

Price Get Latest Price
Package 200kg
Min. Order: 20kg
Supply Ability: 20 tons
Update Time: 2024-10-29

Product Details

Product Name: alpha,alpha-Diphenyl-4-piperidinemethanol CAS No.: 115-46-8
Min. Order: 20kg Purity: 99%
Supply Ability: 20 tons Release date: 2024/10/29

115-46-8 - Physico-chemical Properties

Molecular FormulaC18H21NO
Molar Mass267.37
Density1.0449 (rough estimate)
Melting Point160-163 °C
Boling Point410.55°C (rough estimate)
Flash Point142°C
SolubilityDMSO 53 mg/mL Water 2 mg/mL Ethanol 53 mg/mL
Vapor Presure0Pa at 25℃
AppearanceSolid
ColorWhite to light beige
pKa13.32±0.29(Predicted)
Storage ConditionStore below +30°C.
Refractive Index1.5100 (estimate)
MDLMFCD00066980
In vitro studyAzacyclonol is formed in human intestinal microsomes and is linearly related to time up to 60 min. The rate of Azacyclonol formation was increased linearly by microsomal protein concentration to 2 mg/ml. The apparent K m and V max values of Azacyclonol on human liver microsomes are 0.82 μm and 60 pmol/min/mg, respectively. The formation of Azacyclonol and Terfenadine Alcohol from Terfenadine is mainly caused by CYP3A(4) the ratio of the rate of formation of isoenzyme catalysis, Terfenadine Alcohol and Azacyclonol is 3:1. After Rifampin administration, the amount of Azacyclonol eliminated by the kidneys increased on average 2-fold.
In vivo studyAzacyclonol (I. V.) affects the response of the blink membrane to postganglionic and preganglionic stimuli. The transmission activity of Azacyclonol in the superior cervical ganglion of the cat was 6.63%.


Company Profile Introduction

Qingdao RENAS Polymer Material Co., Ltd. is located in E.T.D.Z of Qingdao China, it is one integrated company, devoted to environmental protection and low carbon energy, new materials introducing, research and development, which aims to offer the best quality products and service to the domestic and foreign markets. We maintain a good partnership with many word famous chemical manufacturers. Integrated of advanced products and technology of domestic and foreign manufacturers, we could customize the products matching scheme for various industries customers, and offer the comprehensive solution to customers. We have unique technology and product advantages, especial in the field of rubber additive, acrylic monomer, solvent, pharmaceutical intermediates and ink coating resin. We have a professional management, business and technical team, and have passed the ISO9001 system certification. We have passed the fast response ability and reliable product quality. With the mission of "steady development and dedication to China", we adhere to the business philosophy of "the interests of users are our most fundamental interests, and the needs of users are our needs". Through concept innovation, management innovation, technical innovation, market innovation, and product innovation, Strive to make the company an excellent supplier in the field of global chemical materials. We welcome friends all over the world to visit and negotiate with us. We sincerely hope to expand our trade and cooperation based on mutual benefits and realize the mutual prosperity and development.

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  • Since: 2010-04-27
  • Address: No. 18 Qinhuangdao Road, E.T.D.Z of QINGDAO
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