Alpha-lipoic acid is a pale yellow powder crystal, almost odorless. It has low solubility in water, about 1 g/L (20°C). Soluble in 10% NaOH solution, soluble in aliphatic solvents.
Lipoic acid is also called alpha-lipoic acid.
Lipoic acid has one chiral center and therefore has both R and S configurations.
Natural lipoic acid is a white crystal with only R configuration, and only R configuration lipoic acid can be covalently conjugated to a lysine residue through an amide bond to play the function of a coenzyme.
The artificially synthesized lipoic acid is a mixture composed of equal proportions of R configuration and S configuration, and is a pale yellow powdery substance, which is easily soluble in lipid solvents.
Alpha Lipoic Acid is a Powerful Antioxidant.

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