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Postion:Product Catalog >ALK/ROS1 inhibitor 2e HCL
ALK/ROS1 inhibitor 2e HCL
  • ALK/ROS1 inhibitor 2e HCL

ALK/ROS1 inhibitor 2e HCL NEW

Price $195 $440 $648
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: ALK/ROS1 inhibitor 2e HCL Purity: 97.52%
Supply Ability: 10g Release date: 2024/11/15

Product Introduction

Bioactivity

名稱ALK/ROS1 inhibitor 2e HCL
描述ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
體外活性(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide (2e) showed impressive enzyme activity against clinically Crizotinib-resistant ALKL1196M with an IC50 value of 41.3?nM.[1] 2e also showed potent inhibitory activity in about 6-fold superior to Crizotinib (IC50: 104.7?nM vs. 643.5?nM) in Ba/F3 cell line harboring ROS1G2032R.[1]
存儲(chǔ)條件keep away from moisture | Shipping with blue ice.
溶解度DMSO : 50 mg/mL (80.5 mM)
關(guān)鍵字ALK/ROS1 inhibitor 2e HCL
相關(guān)產(chǎn)品Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin
相關(guān)庫經(jīng)典已知活性庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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