Product Details
| Product Name:
Aligeron |
CAS No.:
70713-45-0 |
| Purity:
98.57% |
Supply Ability:
10g |
| Release date:
2024/11/20 |
Product Introduction
Bioactivity
| Name | Aligeron |
| Description | Aligeron, a non-selective prostaglandin (PG) antagonist, inhibits PGF2α- and PGE2-induced blood pressure decreases in cats and can prevent PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats. Additionally, Aligeron is recognized for its antioxidant-protective effect against vascular complications. |
| In vitro | Aligeron demonstrates a wide-ranging spectrum of antagonistic activity against various spasmogens in diverse isolated organs. In experiments conducted on the isolated perfused rabbit artery, the antagonistic effects of Aligeron against the vasoconstrictor impacts of noradrenaline and adrenaline are evident.[1]]
The effect of Aligeronin in vitro lacks selectivity and is probably due to interference with the action of Ca2+.[3] |
| In vivo | Aligeron(5 mg/kg; i.v.) increases cortical resistance to hypoxia and accelerates the recovery of cortical bioelectrical activity In hypoventilation hypoxia. Aligerons show a protective effect in KCl- and AMP-induced depressions manifested, And show a decrease in the degree and duration of the depression.[2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : Soluble
|
| Keywords | Aligeron |
| Inhibitors Related | Angoroside C | Pranoprofen | Tranilast | Benorilate | Rutin | Ozagrel | Ethamsylate | Rebamipide | Evodiamine | Tebufelone | Timapiprant | p-Hydroxycinnamic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States