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Postion:Product Catalog >AG-270
AG-270
  • AG-270

AG-270 NEW

Price $112 $270 $432
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: AG-270 CAS No.: 2201056-66-6
Purity: 98.28% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱AG-270
描述AG-270 is an allosteric and orally active inhibitor of MAT2A.
體外活性AG-270 exhibits an IC50 of 20 nM in HCT116 MTAP-null cell SAM at 72 h[1].AG-270 demonstrates potent reduction in levels of intracellular SAM, as well as MTAP-null–selective antiproliferative activity in the HCT116 MTAP isogenic cell model in vitro[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : <1 mg/mL (insoluble or slightly soluble)
關(guān)鍵字inhibit | Inhibitor | cancer | Low | AG270 | AG 270 | solid | SAM | AG-270 | pancreatic | lymphoma | tumor | toxicity
相關(guān)產(chǎn)品MAT2A-IN-10 | MAT2A-IN-9 | FIDAS-3 | MAT2A inhibitor 4 | MAT2A-IN-12 | MAT2A-IN-11 | MAT2A inhibitor 2 | AGI-25696 | PF-9366
相關(guān)庫(kù)經(jīng)典已知活性庫(kù) | 表觀遺傳庫(kù) | 血液病分子庫(kù) | 抗癌臨床化合物庫(kù) | 藥物功能重定位化合物庫(kù) | 抑制劑庫(kù) | NO PAINS 化合物庫(kù) | 已知活性化合物庫(kù) | 抗癌藥物庫(kù) | 抗癌活性化合物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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