Ac4ManNAz NEW
| Price | $32 | $50 | $80 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: Ac4ManNAz | CAS No.: 361154-30-5 |
| Purity: 98.42% | Supply Ability: 10g |
| Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱(chēng) | Ac4ManNAz |
| 描述 | Ac4ManNAz is an azide-containing metabolic glycoprotein labeling reagent that can selectively modify proteins and can be used for cell labeling, tracking, and proteomic analysis. |
| 體外活性 | METHODS: A549 cells were cultured with 0, 10, and 50 μM Ac4ManNAz, and total RNA was extracted to evaluate the quantity and quality of total RNA. RESULTS Compared with untreated A549 cells, mRNA expression levels changed 7-fold; biological functional pathways related to urogenital cancer and cell invasion were significantly activated, while signal transduction related to cell maturation and surface receptor ligation was inhibited. [1] METHODS: Ac4MAnNAz (0-50 μM) treated A549 cells, and analyzed the channel activation, proliferation ability and vitality of A549 cells treated with Ac4ManNAz; Ac4ManNAz (0, 10, 20, 50 μM, 30 hours) treated A549 cells, and performed wounds on A549 cells Healing and invasion assays. RESULTS There was no significant change in the activities of TRP M7 and VSOR Cl channels, and the growth rate of A549 cells was reduced by 10%; as the concentration of Ac4ManNAz increased, the migration and invasion abilities gradually decreased, [1] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (116.18 mM), Sonication is recommended. |
| 關(guān)鍵字 | glycoprotein | tracking | azido | labeling | Inhibitor | inhibit | Ac4ManNAz | Ac-4ManNAz |
| 相關(guān)產(chǎn)品 | N-Boc-4-pentyne-1-amine | Diethylene glycol bis(p-toluenesulfonate) | 6-Maleimidocapronic acid | Fmoc-8-amino-3,6-dioxaoctanoic acid | Bis-Tos-PEG4 | Boc-NH-PEG4-CH2COOH | 11-Aminoundecanoic acid | 1,3-Dibromo-5,5-dimethylhydantoin | 1-Bromo-6-chlorohexane | 5-Ethynyl-2'-deoxyuridine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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