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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Mitogen-activated protein kinase (MAPK)>p38 MAPK inhibitor>LY2228820
LY2228820
  • LY2228820
  • LY2228820
  • LY2228820

LY2228820

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 200kg
Update Time: 2020-01-13

Product Details

Product Name: LY2228820 CAS No.: 862507-23-1
Min. Order: 1g Purity: 99%
Supply Ability: 200kg Release date: 2020/01/13

Mary

 

Product Name:
LY2228820
Synonyms:
Ralimetinib 2MsOH(LY2228820);LY2228820;5-[2-(1,1-DiMethylethyl)-5-(4-fluorophenyl)-1H-iMidazol-4-yl]-3-(2,2-diMethylpropyl)-3H-iMidazo[4,5-b]pyridin-2-aMine DiMethanesulfonate;LY2228820(LY-2228820);LY2228820 2MsOH;LY2228820 diMesylate;5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate;5-(2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate
CAS:
862507-23-1
MF:
C26H37FN6O6S2
MW:
612.7369832
EINECS:
 
Product Categories:
Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Inhibitors;MAPK
Mol File:
862507-23-1.mol
Article illustration
 
LY2228820 Chemical Properties
 
Safety Information
MSDS Information
 
 
LY2228820 Usage And Synthesis
Uses
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events.
 
LY2228820 Preparation Products And Raw materials

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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