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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Quinoline compounds>8-Hydroxyquinaldine
8-Hydroxyquinaldine
  • 8-Hydroxyquinaldine
  • 8-Hydroxyquinaldine
  • 8-Hydroxyquinaldine
  • 8-Hydroxyquinaldine
  • 8-Hydroxyquinaldine

8-Hydroxyquinaldine NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-10-12

Product Details

Product Name: 8-Hydroxyquinaldine CAS No.: 826-81-3
EC-No.: 212-562-6 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/10/12

CAS:826-81-3
MF:C10H9NO
MW:159.18
EINECS:212-562-6
Product Categories:Alkylquinolines;Hydroxyquinolines;Quinolines, Quinazolines and derivatives;Quinolines;bc0001
Mol File:826-81-3.mol
Article illustration

8-Hydroxyquinaldine Chemical Properties
Melting point 71-73 °C(lit.)
Boiling point 267 °C(lit.)
density 1.1202 (rough estimate)
refractive index 1.6070 (estimate)
Fp 139°C
storage temp. Store below +30°C.
solubility 0.4g/l
pkapK1:5.55(+1);pK2:10.31(0) (25°C)
form Crystalline Powder
color Beige to brown
PH7-8 (100g/l, H2O, 20℃)(slurry)
Water Solubility insoluble
BRN 119194
CAS DataBase Reference826-81-3(CAS DataBase Reference)
NIST Chemistry Reference8-Quinolinol, 2-methyl-(826-81-3)
EPA Substance Registry System8-Quinolinol, 2-methyl- (826-81-3)
8-Hydroxyquinaldine Usage And Synthesis
Chemical Propertiesbeige to brown crystalline powder. Soluble in hot alcohol, ether and benzene, insoluble in water. Can volatilize with water vapor and sublimate at 100℃. With phenol odor.
Uses8-Hydroxyquinaldine is mainly used as metal ion extractant and metal ion determination, also used in the synthesis of dyes and pigments and the preparation of pharmaceutical intermediates.
Preparation8-hydroxyquinaldine is obtained from the reaction of 2-aminophenol with crotonaldehyde. Mix 2-aminophenol and 2-Nitrophenol homogeneously and add hydrochloric acid. Add crotonaldehyde under stirring. Heat for 6h and leave overnight. Distill the reacted o-nitrophenol by water distillation, and add sodium hydroxide solution to the residual solution to make it weakly basic. Then add powdered carbonyls for saturation, and distill 8-Hydroxyquinaldine by water distillation, and then distill the crude product under reduced pressure and recrystallize it with ethanol to obtain 8-hydroxyquinaldine.
DefinitionChEBI: 2-Methylquinolin-8-ol is a hydroxyquinoline.
Synthesis Reference(s)Tetrahedron, 52, p. 2937, 1996 DOI: 10.1016/0040-4020(95)01118-8
General Description2-Methyl-8-quinolinol is a methyl substituted quinolinol derivative that shows fungicidal property. It can also undergo complexation with transition metal complexes.
Purification MethodsCrystallise the quinoline from EtOH or aqueous EtOH. Its solubility at 20o in H2O is 0.366g/L, and in CHCl3 it is 466g/L. It complexes with many metals. [Beilstein 21 H 106, 21 III/IV 2132.]

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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