Motesanib
| Price | $1 |
| Package | 1g |
| Min. Order: | 1g |
| Supply Ability: | 100kgs |
| Update Time: | 2020-01-03 |
Product Details
| Product Name: Motesanib | CAS No.: 453562-69-1 |
| Min. Order: 1g | Purity: 99% |
| Supply Ability: 100kgs | Release date: 2020/01/03 |
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Product Name:
Motesanib
Synonyms:
N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide;3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-;Motesanib Base;AMG-706(Motesanib);Motesanib (AMG-706) Base);motesanib;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
CAS:
453562-69-1
MF:
C22H23N5O
MW:
373.45
EINECS:
Product Categories:
Antineoplastic;Inhibitors;API
Mol File:
453562-69-1.mol
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Motesanib Chemical Properties
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Boiling point
517.3±50.0 °C(Predicted)
density
1.251
form
White powder solid.
pka
11.75±0.40(Predicted)
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Safety Information
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MSDS Information
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Motesanib Usage And Synthesis
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Chemical Properties
Pale Yellow Solid
Uses
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.
Uses
Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.
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Motesanib Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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