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Postion:Product Catalog >API>Antibiotics>Lincosamides Drugs>Clindamycin
Clindamycin
  • Clindamycin

Clindamycin

Price $1
Package 1KG
Min. Order: 1IU
Supply Ability: 100kg
Update Time: 2019-12-25

Product Details

Product Name: Clindamycin CAS No.: 18323-44-9
Min. Order: 1IU Purity: 99%
Supply Ability: 100kg Release date: 2019/12/25
name: Cassie180
Product Name:
Clindamycin
Synonyms:
Clindamycin (base and/or unspecified salts);(2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;CLDM;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S)-1-methyl-4β-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;U-21251;Clindamycin Base;7-Chloro-7-deoxylincoMycin, 7-ChlorolincoMycin
CAS:
18323-44-9
MF:
C18H33ClN2O5S
MW:
424.98
EINECS:
242-209-1
Product Categories:
-;Inhibitors
Mol File:
18323-44-9.mol
Article illustration
 
Clindamycin Chemical Properties
alpha 
D +214° (chloroform)
Boiling point 
134°C (rough estimate)
density 
1.1184 (rough estimate)
refractive index 
1.6100 (estimate)
pka
7.6(at 25℃)
CAS DataBase Reference
18323-44-9(CAS DataBase Reference)
EPA Substance Registry System
L-threo-?-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- (18323-44-9)
 
Safety Information
Hazardous Substances Data
18323-44-9(Hazardous Substances Data)
Toxicity
LD50 subcutaneous in rat: 2618mg/kg
MSDS Information
 
 
Clindamycin Usage And Synthesis
Uses
Clindamycin is a semi-synthetic analogue of lincomycin, prepared by chloride substitution of the exocyclic sugar hydroxy group. This affords a more hydrophobic compound with improved pharmacodynamics. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin has been extensively studied with over 8,000 literature citations.
Definition
ChEBI: A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic.
Brand name
Cleocin (Pharmacia & Upjohn).
Contact allergens
This lincosanide antibiotic is used in topical form for acne, or systemically has been responsible for exanthematous rashes and acute generalized exanthematous pustulosis.
Veterinary Drugs and Treatments
Topical clindamycin is an optional topical treatment for feline acne.
Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosome; primary activity is against anaerobic and grampositive aerobic bacteria. For more information on the pharmacology of clindamycin, refer to the monograph for systemic use found in the main section.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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