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Postion:Product Catalog >7α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one
  • 7α-Hydroxy-4-cholesten-3-one

7α-Hydroxy-4-cholesten-3-one NEW

Price $289 $698 $968
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: 7α-Hydroxy-4-cholesten-3-one CAS No.: 3862-25-7
Purity: 99.14% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱7α-Hydroxy-4-cholesten-3-one
描述7α-Hydroxy-4-cholesten-3-one is an intermediate in bile acid synthesis from cholesterol, a PXR agonist, and a biomarker for bile acid loss and diseases related to defective bile acid biosynthesis. It is also the physiological substrate for [CYP8B1].
體外活性7α-Hydroxy-4-cholesten-3-one is a key intermediate in the bile acid synthesis pathway. Cytochrome P450 7A1 introduces a 7α-hydroxy group to cholesterol, and 3β-hydroxysteroid dehydrogenase then oxidizes and isomerizes the 3-hydroxy group and the Δ5,6-double bond, forming 7α-Hydroxy-4-cholesten-3-one. The absence of P450 27A1 downstream increases its concentration [1].
體內(nèi)活性7α-Hydroxy-4-cholesten-3-one significantly influences the hepatic enzyme CYP7A1 activity under steady-state conditions and during rapid diurnal fluctuations in rats. Moreover, its serum levels exhibit a marked diurnal rhythm.
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 80 mg/mL (199.68 mM), Sonication is recommended.
關(guān)鍵字7αHydroxy4cholesten3one | 7α Hydroxy 4 cholesten 3 one | 7alpha-Hydroxy-4-cholesten-3-one | 7a-Hydroxy-4-cholesten-3-one | 7α-Hydroxy-4-cholesten-3-one

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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